Scientific Program

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24 August 2016   25 August 2016   26 August 2016  27 August 2016  28 August 2016


 

Wednesday, 24 August 2016

Opening Plenary

5:00 pm - 6:30 pm

Moderators:  Michael Ison, MD, MS and Lance Jennings, QSO, PhD

5:00 pm - 5:15 pm Welcome from the ISIRV President
  Lance Jennings, QSO, PhD 
Cantebury Laboratories
Christchurch, New Zealand
5:15 pm - 5:30 pm  Welcome from Options Organizing Chair
  Michael G. Ison, MD, MS
Infectious Diseases and Organ Transplantation
Northwestern University Feinberg School of Medicine
Chicago, IL, United States
5:30 pm - 6:30 pm Keynote Address
  Nancy J. Cox, PhD
Past Director of the Influenza Division at the Centers for Disease Control and Prevention (CDC) 
and Director of CDC’s World Health Organization (WHO) Collaborating Center for Surveillance, 
Epidemiology and Control of Influenza 
 

Welcome Reception in the Exhibit Hall

6:30 pm - 8:00 pm

 

Thursday, 25 August 2016

Late Breaking Oral Abstract Session: Public Health

8:00 am – 8:30 am

Moderators:  Ben Cowling, BSc, PhD and Jonathan Nguyen-Van-Tam, DM, FRCPath

Public Health Plenary Session: Addressing the Public Health Threat of Influenza:  Recognition, Prevention and Treatment

8:30 am – 10:30 am

Moderators:  Ben Cowling, BSc, PhD and Jonathan Nguyen-Van-Tam, DM, FRCPath

8:30 am – 9:10 am     Outbreak and Pandemic Response:  Role of Antivirals 
 

Nahoko Shindo, MD, PhD
World Health Organization
Geneva, Switzerland

9:10 am – 9:50 am   Exposure to Influenza in the Healthcare Environment
  Werner Bischoff, MD, PhD

Wake Forest Baptist Medical Center
Salem, NC, United States

9:50 am – 10:30 am

The Market as an Influenza Risk Factor: The Animal Human Interface

  Yuelong Shu, PhD
National Institute for Viral Disease Control and Prevention, China CDC
Beijing, People's Republic of China

Coffee Break in the Exhibit Hall

10:30 am – 11:00 am

Concurrent Oral Abstract Sessions

11:00 am – 12:30 pm

  • Public Health
    Moderators:  Udo Buchholz, MD, MPH and Michael Cooper, PhD 
  • Virology & Pathogenesis
    Moderators:  Justin Bahl, PhD and Erhard Van der Vries, PhD
  • Clinical Science
    Moderators:  Jane Ryan, PhD and Norio Sugaya, MD, PhD

Sponsored Lunch Satellite Symposium
Dissecting the Influenza Challenge: Perspectives on Prevention and Management

Supported by Seqirus

12:30 pm – 2:00 pm
View Program & Register

Open to all registered attendees

Concurrent Featured Symposia

2:00 pm – 4:00 pm

Clinical Science Featured Symposia: Diagnostic and Monitoring Tools in the Clinical Setting

Moderators:  Rich Wunderink, MD and David Smith, MBBS, FRCPA

 2:00 pm – 2:30 pm  Rapid Diagnosis for Influenza and Other Respiratory Viruses
  Maria Zambon, BSc, PhD
Public Health England
London, United Kingdom
2:30 pm – 3:00 pm Role of Biomarkers (Differentiating Viral From Bacterial/Mixed Infections)
  Ann Falsey, MD
University of Rochester School of Medicine
Rochester, NY, United States
3:00 pm – 3:30 pm Detection of Antiviral Resistance
  Aeron Hurt, PhD
WHO Collaborating Centre for Reference and Research on Influenza, Melbourne
Melbourne, Victoria, Australia
3:30 pm – 4:00 pm Prognostic Indicators in Severe Influenza
  William Jake Dunning, MRCP, PhD
Public Health England
London, United Kingdom

Public Health Featured Symposia: Pandemic Preparedness

Moderators:  Dan Jernigan, MD, MPH and Peter Horby, MD, PhD

2:00 pm – 2:30 pm  Pandemic Planning – Where are We?
  Wenqing Zhang, MD
World Health Organization
Geneva, Switzerland
2:30 pm – 3:00 pm Effectiveness of Antivirals
  Jonathan Nguyen-Van-Tam, DM FRCPath
University of Nottingham, School of Medicine
Nottingham, United Kingdom
3:00 pm – 3:30 pm Pandemic and Pre-pandemic Vaccines, Where Are We Now?
  Rick A. Bright, PhD
HHS/OS/ASPR/BARDA
Washington DC, United States
3:30 pm – 4:00 pm Implementation and Impact of Non-Pharmaceutical Interventions in the 20th Century Pandemics
 

Amra Uzicanin, MD‚ MPH
Centers for Disease Control and Prevention (CDC)
Atlanta, GA, United States

Virology & Pathogenesis Featured Symposia: Virus Host-Cell Interactions

Moderators:  Stacey Schultz-Cherry, PhD and Wendy Barclay, MA, PhD

2:00 pm – 2:30 pm  Antiviral Innate Immune Responses to Influenza Viruses
  Adolfo Garcia-Sastre, PhD
Icahn School of Medicine at Mount Sinai
New York, NY, United States
2:30 pm – 3:00 pm Influenza A Virus Uncoating Mechanisms
  Yohei Yamauchi, MD, PhD
University of Zurich
Zurich, Switzerland
3:00 pm – 3:30 pm IFITM3 Restriction of Viral Replication
  Abraham Brass, MD PhD
University of Massachusetts Medical School
Newton, MA, United States 
3:30 pm – 4:00 pm Influenza Virus Interference with Innate Immunity
  Christina Ehrhardt, PhD
Westfaelische Wilhelms-University Muenster / Institute of Molecular Virology
Muenster, North Rhine-Westphalia, Germany

Coffee Break in the Exhibit Hall

4:00 pm - 4:30 pm

Concurrent Oral Abstract Sessions

4:30 pm - 6:00 pm

  • Public Health I
    Moderators: Rebecca Cox, PhD and  Vernon Lee, MBBS, PhD 
  • Public Health II
    Moderators: John Watson, MD, FRCP and ​Hitoshi Oshitani, MD, PhD
  • Virology & Pathogenesis

    Moderators:  Julie McAuley, PhD and Ab Osterhaus

Poster Session with Presenters in Attendance

6:00 pm - 7:30 pm

  • Public Health Theme:  6 min rapid abstract (10 Abstracts)
  • Virology & Pathogenesis Theme:  6 min rapid abstract (10 Abstracts)
  • Clinical Science Theme:  6 min rapid abstract (10 Abstracts)

ISIRV Epidemiology Panel

“Leveraging influenza surveillance infrastructure for the monitoring of non-influenza respiratory viruses”

7.30 pm - 8:30pm

Room Location:  Michigan B, Level 2

 

Friday, 26 August 2016

Virology & Pathogenesis Plenary Session: Molecular Studies for Vaccines and Antivirals

8:00 am – 10:00 am    

Moderators:  Jackie Katz, PhD and Robert Lamb, PhD, ScD

8:00 am – 8:40 am Structure, Mechanism and Drug Targeting of Influenza Polymerase
  Stephen Cusack, PhD, FRS
European Molecular Biology Laboratory, Grenoble Outstation
Grenoble, France
8:40 am – 9:20 am Toward A Universal Influenza Virus Vaccine
  Peter Palese
Icahn School of Medicine at Mount Sinai
New York, NY, United States
9:20 am – 10:00 am Influenza Countermeasures
  Yoshihiro Kawaoka, DVM, PhD
University of Wisconsin-Madison/University of Tokyo
Madison, WI, United States

ISIRV General Meeting

10:00 am – 10:45 am

Coffee Break in the Exhibit Hall

10:45 am - 11:15 am

Concurrent Oral Abstract Sessions

11:15 am - 12:30 pm

  • Public Health
    Moderators: Arnold Monto, MD and Sheena Sullivan, MPH, PhD
  • Virology & Pathogenesis
    Moderators: 
    Hassan Zaraket, BS Pharm, PhD and Andrew Pavia, MD
  • Clinical Science
    Moderators:
    Regina Dutkowki and Ann Falsey, MD

Sponsored Lunch Satellite Symposium

Influenza Vaccination in Children - Cost and Benefit

Supported by AstraZeneca

12:30 pm – 2:00 pm

View Program & Register

Open to all registered attendees

Concurrent Featured Symposia

2:00 pm – 4:00 pm

Clinical Science Featured Symposia: Management of Influenza in Unique Populations

Moderators:  Tim Uyeki, MD, MPH and Ann Falsey, MD  

2:00 pm – 2:30 pm Pediatrics
  Norio Sugaya, MD, PhD
Department of Pediatrics, Keiyu Hospital
Nishi-ku, Yokohama, Kanagawa, Japan
2:30 pm – 3:00 pm Immunocompromised
  Roy F. Chemaly, MD, MPH
University of Texas MD Anderson Cancer Center
Houston, TX, United States
3:00 pm – 3:30 pm Critical Care
  John C. Marshall
University of Toronto/St. Michael's Hospital
Toronto, ON, Canada
3:30 pm – 4:00 pm Elderly
  Janet McElhaney, MD
Advanced Medical Research Institute of Canada
Sudbury, ON, Canada

Public Health Featured Symposia: Influenza Vaccines

Moderators:  Kathy Neuzil, MD, MPH and Alain Moren, MD, PhD

2:00 pm – 2:30 pm Contemporary Approaches to Estimation of Influenza Vaccine Effectiveness
  Alain Michel Moren, MD, PhD
EpiConcept
Paris, France
2:30 pm – 3:00 pm Vaccine Effectiveness and Repeated Vaccination: Too Much of a Good Thing?
  Edward A. Belongia, MD
Marshfield Clinic Research Foundation
Marshfield, WI, United States
3:00 pm – 3:30 pm In-season Waning of Vaccine Effectiveness: European Influenza Type/subtype-Specific Vaccine Effectiveness Data From 6 Seasons
  Esther Kissling, MSc, BSc hons
EpiConcept
Paris, France
3:30 pm – 4:00 pm Implications of Timely Vaccine Effectiveness Estimates for Vaccine Strain Selection 
  Alicia Fry, MD, MPH
CDC
Atlanta, GA, United States

Virology & Pathogenesis Featured Symposia: Pathogenesis

Moderators:  Mark Tompkins, PhD and Yoshihiro Kawaoka, DVM, PhD

2:00 pm – 2:30 pm Pathogenesis of HA structures
  George Gao, DPhil
Immunology, Institute of Microbiology, Chinese Academy of Sciences
Beijing, People's Republic of China
2:30 pm – 3:00 pm HA Acid Stability in Pathogenesis and Host Adaptation
  Charles John Russell, PhD
St. Jude Children's Research Hospital
Memphis, TN, United States
3:00 pm – 3:30 pm  Influenza A Virus Evolution: Going Deep
  Jonathan Yewdell, MD, PhD
LVD, NIAID
Bethesda, MD, United States
3:30 pm – 4:00 pm Transmission of Influenza Virus
  Malik Peiris, MD, DPhil
School of Public Healh, The University of Hong Kong
Pokfulam, Hong Kong

Coffee Break in the Exhibit Hall

4:00 pm - 4:30 pm

Concurrent Oral Abstract Sessions

4:30 pm - 6:00 pm

  • Public Health
    Moderators: Carrie Reed, DSc, MPH and Danuta Skowronski, MD, MHSc
  • Virology & Pathogenesis I
    Moderators: Stephanie Bertram and Barbara Rath, MD, PhD
  • Virology & Pathogenesis II
    Moderators:
    Erhard Van der Vries, PhD and Adolfo Garcia-Sastre, PhD

Poster Session with Presenters in Attendance

6:00 pm - 7:30 pm

  • Public Health Theme: 6 min rapid abstract (10 Abstracts)
  • Virology & Pathogenesis Theme: 6 min rapid abstract (10 Abstracts)
  • Clinical Science Theme: 6 min rapid abstract (10 Abstracts)
 

Saturday, 27 August 2016

Clinical Science Plenary Session: Newer Therapies for Influenza:  Hurdles and Progress

8:30 am - 10:30 am

Moderators:  Melissa Willis, PhD and Nelson Lee, MD, FRCP

8:30 am – 9:10 am    Clinical Development Challenges: Trial Designs and Endpoints
 

Menno de Jong, MD, PhD
University of Amsterdam
Amsterdam, The Netherlands

9:10 am – 9:50 am     Novel Antiviral Agents in Advanced Development
 

Frederick Hayden, MD
University of Virginia School of Medicine
Charlottesville, VA, United States

9:50 am – 10:30 am  Combination and Antibody-Based Therapies
 

John Beigel, MD
Leidos/NIAID
Bethesda, MD, United States

Coffee Break in the Exhibit Hall

10:30 am - 11:00 am

Concurrent Oral Abstract Sessions

11:00 am - 12:30 pm

  • Public Health
    Moderators: Cecile Viboud, PhD and Tim Uyeki, MD, MPH
  • Virology & Pathogenesis
    Moderators: Julie McAuley, PhD and Ruben Donis, PhD
  • Clinical Science
    Moderators: Larisa Gubareva, MD, PhD and Janet McElhaney, MD, FRCPC, FACP

Sponsored Lunch Satellite Symposium
Respiratory Syncytial Virus: An Underrecognized Health Burden in Older Adults

Supported by Novavax

12:30 pm – 2:00 pm

View Program & Register

Open to all registered attendees

Concurrent Featured Symposia

2:00 pm – 4:00 pm   

Clinical Science Featured Symposia: Complications of Influenza

Moderators:  Roy Chemaly, MD, MPH and Menno de Jong, MD, PhD

2:00 pm – 2:30 pm Bacterial Co-Infection
  Richard Glenn Wunderink, MD
Northwestern University Feinberg School of Medicine
Chicago, IL, United States
2:30 pm – 3:00 pm Cardiovascular Complications
  Charlotte Warren-Gash, MRCP, PhD
Institute of Health Informatics, University College London
London, United Kingdom
3:00 pm – 3:30 pm Neurological Complications
  Mizuguchi Masashi, MD, PhD
Dept. of Developmental Medical Sciences, Graduate School of Medicine, The University of Tokyo
Tokyo, Japan
3:30 pm – 4:00 pm  Exacerbation of Airway Diseases
  Peter Openshaw, MD, PhD
Imperial College London
London, United Kingdom

Public Health Featured Symposia: Epidemiology of Influenza

Moderators:  Jean-Michel Héraud, PhD, HDR and Carrie Reed, DSc, MPH

2:00 pm – 2:30 pm Incidence of Infection, Illness and Burden of Disease
  Cecile Viboud, PhD
Fogarty International Center, NIH, USA
Bethesda, MD, United States
2:30 pm – 3:00 pm Comparative Epidemiology of Influenza A Subtypes
  Arnold Monto, MD
School of Public Health, University of Michigan
MI, United States
3:00 pm – 3:30 pm Comparative Epidemiology of Influenza B Lineages 
  Vijaykrishna Dhanasekaran, PhD
Duke-NUS Medical School Singapore
Singapore
3:30 pm – 4:00 pm Population Impact of a Pediatric Vaccination Policy
  Richard Pebody, MBChB, PhD
Public Health England
London, United Kingdom

Virology & Pathogenesis Featured Symposia: Replication of Influenza

Moderators:  Guy Boivin, MD and Aeron Hurt, PhD

2:00 pm – 2:30 pm  Influenza Virus Reassortment
  Anice Lowen, PhD
Emory University
Atlanta, GA, United States
2:30 pm – 3:00 pm The Biology of Influenza Virus non-coding RNAs
  Benjamin tenOver, PhD
Icahn School of Medicine
NY, United States
3:00 pm – 3:30 pm Transcription and Replication of the Influenza Virus RNA Genome
  Ervin Fodor, DPhil
University of Oxford
Oxford, United Kingdom
3:30 pm – 4:00 pm Constraints on the Evolution of Influenza
  Jesse Bloom, PhD
Fred Hutchinson Cancer Research Center
Seattle, WA, United States

Coffee Break in the Exhibit Hall

4:00 pm - 4:30 pm

Oral Abstract Session

4:30 pm - 6:00 pm

  • Virology & Pathogenesis
    Moderators:
      Alan Hay, PhD and Matthew Memoli, MD, MS

Public Health/Clinical Science Pregnancy Symposium

4:30 pm – 6:00 pm

Moderators:  Nelson Lee, MD, FRCP and Jonathan Nguyen-Van-Tam, DM, FRCPath

4:30 pm – 4:50 pm Epidemiology of Influenza in the Pregnant Female
 

Brad Gessner, MD, MPH
Agence de Medecin Preventive
Paris, France

4:50 pm – 5:10 pm

Maternal Influenza and Birth Outcomes

  Deshayne Fell, MSc
Children's Hospital of Eastern Ontario Research Institute
ON, Canada
5:10 pm – 5:30 pm Safety and Efficacy of Influenza Vaccine in Pregnant Women and the Young Infant
  Janet Englund, MD
Univ. Washington/Seattle Children's Hospital
Seattle, WA, United States
5:30 pm – 5:50 pm Antiviral Therapy in Pregnancy
  Tim Uyeki, MD, MPH

Influenza Division, U.S. Centers For Disease Control And Prevention
Atlanta, GA, United States

5:50 pm – 6:00 pm Q&A Panel

Poster Session with Presenters in Attendance

6:00 pm - 7:30 pm

Offsite Event:*  Mystic Blue Boat Cruise

*Separate Registration Fee to Attend

7:45 pm – 11:30 pm

Sunday, 28 August 2016 

Late Breaking Oral Abstract Session

8:00 am – 8:30 am

Moderators:  Michael Ison, MD, MS and Lance Jennings, PhD

Concurrent Featured Symposia

8:30 am – 10:30 am  

Clinical Science Featured Symposia: Addressing Therapeutic Challenges

Moderators:  Natasha Halasa, MD, MPH and Bin Cao, MD

8:30 am – 9:00 am  Managing Avian Influenza (H7N9, H5N1)
  Zhancheng Gao, MD, PhD
Peking University People’s Hospital, Beijing, China
Beijing, China
9:00 am – 9:30 am Adjuvant and Immune-Modulatory Therapies
  David Shu-Cheong Hui, MD
The Chinese University of Hong Kong
Shatin, New Territories, Hong Kong
9:30 am – 10:00 am Resistance Emergence During Therapy
  Erhard Van der Vries, PhD
TiHo - Research Center for Emerging Infections and Zoonoses
Hannover, Lower Sachsony, Germany
10:00 am – 10:30 am Rapid Access to Antivirals and Cost-Effectiveness
 

Martin Meltzer
Centers for Disease Control and Prevention (CDC)
Atlanta, GA, United States

Public Health Featured Symposia: Practical Issues in the Control of Influenza

Moderators:  Terho Heikkinen, MD, PhD and Ruth Lynfield, MD

8:30 am – 9:00 am  Outbreak Control in Residential Care Homes
  Marianne A.B. van der Sande, MD, PhD
Centre for Infectious Disease Control, National Institute for Public Health and the Environment, the Netherlands
Bilthoven, Utrecht, Netherlands
9:00 am – 9:30 am Early Use of Antiviral Drugs
  Allison McGeer, MD, FRCPC
Mount SInai Hospital, University of Toronto
Toronto, ON, Canada
9:30 am – 10:00 am Mandatory Vaccination of Health Care Workers
  Helena Maltezou, MD, PhD
Hellenic Center for Disease Control and Prevention
Athens, Greece
10:00 am – 10:30 am Improving Vaccine Uptake in Target Groups
  Darina O'Flanagan, MB, MPH
Health Protection Surveillance Centre Ireland
Castleknock, Ireland

Virology & Pathogenesis Featured Symposia: Immunology

Moderators:  Leo Poon, DPhil and Patrick Reading, PhD

8:30 am – 9:00 am Cross-talk Between an Epithelial Integrin and Alveolar Macrophages Regulates the Lung Response to Influenza Infection
  Stacey Lynne Schultz-Cherry, PhD
St Jude Children's Research Hospital
Memphis, TN, United States
9:00 am – 9:30 am Genetic and Structural Basis for Antibody-Mediated Neutralization of Influenza
  James Crowe, MD
Vanderbilt University
Nashville, TN, United States
9:30 am – 10:00 am  ³CD8+ T cells and recovery from severe H7N9 disease²
  Katherine Kedzierska, PhD
University of Melbourne; Peter Doherty Institute
Melbourne, Vic, Australia
10:00 am – 10:30 am  Evasion of Human Influenza A Viruses from Recognition by T Cells
  Guus Rimmelzwaan, MSc, PhD
Erasmus Medical Center
Rotterdam, Netherlands

Coffee Break 

10:30 am - 11:00 am

Concurrent Oral Abstract Sessions

11:00 am - 12:30 pm

  • Public Health
    Moderators: Lone Simonsen, PhD and Kimberly Armstrong, PhD
  • Virology & Pathogenesis
    Moderators: David Wentworth, MS, PhD and David Jackson, BSc, PhD
  • Clinical Science
    Moderators: Angela Campbell, MD, MPH and Fred Aoki, MD

Lunch Break

12:30 pm - 1:00 pm

Closing Plenary Session - The Future Threats from Influenza

1:00 pm - 3:00 pm

Moderators:  Michael Ison, MD, MS and Lance Jennings, PhD

1:00 pm – 1:40 pm Influenza at the Animal-Human Interface
 

David Swayne, DVM, PhD
Agricultural Research Service, U.S. Department of Agriculture
Athens, GA, United States

1:40 pm – 2:20 pm

Forecasting the Future of Flu 

  Trevor Bedford, PhD
Fred Hutchinson Cancer Research Center
Seattle, WA, United States
2:20 pm – 3:00 pm

Improving on Influenza Vaccines: Managing the Challenges of Vaccine Mismatch

  Dan Jernigan, MD, MPH
US Centers for Disease Control and Prevention
Atlanta, GA, United States